Electroencephalographic effects of chlorphenesin carbamate, a new central muscle relaxant, in rabbits
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چکیده
منابع مشابه
Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats.
The effects of chlorphenesin carbamate (CPC) and mephenesin on spinal neurons were investigated in spinal rats. CPC (50 mg/kg i.v.) inhibited the mono-(MSR) and poly-synaptic reflex (PSR), the latter being more susceptible than the former to CPC depression. Mephenesin also inhibited MSR and PSR, though the effects were short in duration. CPC had no effect on the dorsal root potential evoked by ...
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Motor depressant effects of diazepam were studied in the intact, decerebrate and high spinal cat. Diazepam (0.125516 mg/kg, i.v.) produced a depression of both the patellar and linguomandibular reflexes in the intact cat. In the high spinal (Cl) cat only the linguomandibular reflex was depressed. Facilitation and inhibition of the patellar reflex elicited in both intact and high spinal (Cl) cat...
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Studies were carried out to elucidate the mechanism of action of chlorphenesin carbamate (CPC) and to compare the effect of the drug with that of mephenesin on the isolated bullfrog spinal cord. Ventral and dorsal root potentials were recorded by means of the sucrose-gap method. CPC caused marked hyperpolarizations and depressed spontaneous activities in both of the primary afferent terminals (...
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15 صفحه اولAnticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1977
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.73.479